| 【Name】 | Common Name: Gemcitabine Hydrochloride for InjectionBrand Name: ZeFeiEnglish name: Gemcitabine Hydrochloride for InjectionChinese Pinyin: Zhusheyong Yansuan Jixitabi |
|---|---|
| 【Ingredients】 | The main ingredient of this product is gemcitabine hydrochloride.Chemical name: (+) 2 ́-deoxy-2 ́, 2 ́- difluorocytidine monohydrochloride.Structural Formula:
Molecular formula: C9H11F2N3O4•HCl Molecular weight: 299.70Excipients: mannitol, sodium acetate |
| 【Description】 | This product is a white solid. |
| 【Indications】 | For the treatment of advanced non-small cell lung cancer, breast cancer and pancreatic cancer. |
| 【Strength】 | 1.0g(Calculated on gemcitabine) |
| 【Dosage and Administration】 | The recommended dose of Gemcitabine for adult is 1000 mg/m2 as an intravenous infusion over 30 minutes once a week for three consecutive weeks, followed by a week of rest, repeated every four weeks. The dose is reduced accordingly according to the patient's toxicity. Preparation method:🌟 Add at least 25 mL of 0.9% Sodium Chloride Injection to t♚he vial (containing gemcitabine 1.0 g), the dilution yields a gemcitabine concentration of not more than 40 mg/mL, shake to dissolve. Prior to administration the required amount of drug must be diluted with 0.9% Sodium Chloride Injection.The prepared gemcitabine solution should be stored at room temperature and used within 24 hours. The gemcitabine solution should not be refrigerated to prevent crystal precipitation.Geriatric Use: Older patients over the age of 65 can also be well tolerated. Although age has an effect on the clearanꦿce and half-life of gemcitabine🀅, there is no evidence that older patients need to adjust the dose. Pediatric Use: The safety and effectiveness💮 of gemcitabine have not been established in pediatric patients. |
